![]() ![]() © 2018 The American Laryngological, Rhinological and Otological Society, Inc. Oral cavity cancer neck dissection sentinel lymph node biopsy squamous cell carcinoma. Despite these attributes, SLNB remains rarely used in the United States. SLNB for stage I to II OCSCC is associated with reduced length of hospital stay and equivalent overall survival compared with END. After adjustment, overall survival was equivalent between patients who underwent SLNB versus END (adjusted hazard ratio 1.03, confidence interval 0.67-1.59). Overall 3-year survival was 82.0% after SLNB and 77.5% after END (P = 0.40). However, the role of SLNB in this scenario is debatable. A comprehensive and systematic literature review was performed by searching the Embase and PubMed databases for English language articles published up to December 2016. Sentinel lymph node biopsy (SLNB) is an emerging strategy for managing early-stage oral squamous cell carcinoma (SCC) with a clinically N0 (cN0) neck. ![]() To address this uncertainty, we collected clinical data on six patients. The role of sentinel lymph node (SLN) biopsy in these patients remains unclear. Perioperative 30-day mortality was 0% after SLNB versus 0.7% after END (P = 0.42). The aim of this study was to systematically evaluate the diagnostic value of the sentinel lymph node biopsy (SLNB) for cT1/T2N0 tongue squamous cell carcinoma (TSCC) patients. High-risk cutaneous squamous cell carcinoma (SCC) is associated with an increased risk of metastases. SLNB was associated with reduced perioperative morbidity, with median length of hospital stay of 1.0 days versus 3.0 days after END (P < 0.001). Completion neck dissection was avoided in 63.8% of patients undergoing SLNB. There have been clinical studies on the sentinel lymph node biopsy for the head and neck squamous cell carcinoma, in which the diagnostic accuracy has been. SLNB was used for 240 patients, or 2.9% of stage I to II OCSCC. We identified 8,328 eligible patients with a median follow-up of 35.4 months. We compared the practice patterns and outcomes of patients who underwent SLNB versus END. We conducted a retrospective cohort study of patients with stage I to II OCSCC (cT1-2cN0cM0) who underwent staging of the neck in the National Cancer Data Base from 2012 to 2015. Based on the AJCC-8 criteria positivity rates in the T2 and T3 categories were 8.3 (1/12 patients) and 25 (8/32), respectively. Results: In total, 153 patients with 24 positive SLN biopsies (15.7) were included. However, utilization of SLNB in the United States remains unclear, and existing prospective studies did not directly compare survival between SLNB and END. Methods: Systematic review of studies of patients with cSCC who underwent SLN biopsy that described biopsy results. Sentinel lymph node biopsy (SLNB) has been shown to be an accurate technique for staging the neck in early-stage oral cavity squamous cell carcinoma (OCSCC) and has been incorporated in treatment guidelines as an option instead of elective neck dissection (END). ![]()
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